Wednesday, October 14, 2020

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Tuesday, October 13, 2020

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Monday, October 12, 2020

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Sunday, October 11, 2020

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Saturday, October 10, 2020

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Friday, October 9, 2020

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Wednesday, October 7, 2020

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Tuesday, October 6, 2020

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Monday, October 5, 2020

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Sunday, October 4, 2020

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Saturday, October 3, 2020

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Friday, October 2, 2020

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Thursday, October 1, 2020

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Wednesday, September 30, 2020

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Saturday, September 26, 2020

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Friday, September 25, 2020

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Thursday, September 24, 2020

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Wednesday, September 23, 2020

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Tuesday, September 22, 2020

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Monday, September 21, 2020

National Cancer Institute

National Cancer Institute November 27, 2007â€"A new model for calculating invasive breast cancer threat was discovered to provide higher estimates of the variety of breast cancers that might develop in African American girls 50 to 79 years of age than an earlier mannequin which was based totally on information from white women. That scientific quest led to the vaccine Gardasil (human papillomavirus vaccine, quadrivalent), which protects in opposition to an infection from the two kinds of human papillomavirus that trigger nearly all of cervical cancers worldwide. May 23, 2006â€"The Trial Assigning Individualized Options for Treatment or TAILORx was launched to look at whether or not genes that are frequently associated with risk of recurrence for women with early-stage breast most cancers can be used to assign sufferers to essentially the most appropriate and efficient therapy. September 28, 2005â€"NCI and the National Institute of Neurological Disorders and Stroke created Rembrandt , a joint informatics initi ative to molecularly characterize numerous primary brain tumors and to correlate these information with intensive retrospective and potential medical information. In addition to serving as Director of NCI, Dr. Sharpless continues his analysis in understanding the biology of the aging course of that promotes the conversion of normal self-renewing cells into dysfunctional most cancers cells. Dr. Sharpless has made seminal contributions to the understanding of the relationship between aging and most cancers, and within the preclinical growth of novel therapeutics for melanoma, lung cancer, and breast most cancers. Researchers at NCI intend to make use of this approach to seek out new, simpler treatments for varied sorts of most cancers primarily based on elevated knowledge of the genetics and biology of the disease and scientists hope to apply precision drugs to all areas of health and healthcare. March 5, 2014â€"Ten winners of a world-wide competition to bring rising breast cancer research technologies to market sooner had been introduced right now by the Avon Foundation for Women, in partnership with the NCI, and the Center for Advancing Innovation . June 29, 2011â€"An evaluation of genomic changes in ovarian cancer has offered probably the most complete and integrated view of most cancers genes for any most cancers kind thus far. Ovarian serous adenocarcinoma tumors from 500 sufferers had been examined by The Cancer Genome Atlas Research Network. November thirteen, 2013â€"A trial carried out by researchers at NCI confirmed grownup patients with a kind of most cancers often known as Burkitt lymphoma had wonderful long-term survival ratesâ€"upwards of ninety percentâ€"following remedy with low-intensity chemotherapy regimens. Standard remedy for Burkitt lymphoma entails high-dose chemotherapy, which has a excessive fee of toxicity, together with demise, and cures solely 60 % of adult patients. September 27, 2012â€"Scientists might have discovered why a protein referred to as MYC can provoke a variety of cancers. Like many proteins related to cancer, MYC helps regulate cell progress. A study carried out by researchers at NIH and colleagues discovered that, in contrast to many other cell progress regulators, MYC does not flip genes on or off, but instead boosts the expression of genes which are already turned on. May 21, 2012â€"In a study that spanned 20 years, the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, sponsored by NCI, discovered that sigmoidoscopy is effective in decreasing the rates of recent cases and deaths because of colorectal cancer. Researchers discovered that overall colorectal most cancers mortality was decreased by 26% and incidence was decreased by 21% because of screening with sigmoidoscopy. March 8, 2012â€"In a brand new examination of United States cancer incidence information, investigators reported that incidence trends have remained roughly constant for glioma, the principle type of brain cancer hypothesized to be related to cell phone use. December 7, 2016â€"In a study of an immune remedy for colorectal cancer that concerned a single affected person, researchers identified a way for targeting the cancer-inflicting protein produced by a mutant form of the KRAS gene. The report was presented by the BRP to the National Cancer Advisory Board , and it was subsequently thought of and accepted by the NCAB with revisions that reflect NCAB’s dialogue. January 12, 2016â€"During his 2016 State of the Union Address, President Obama called on Vice President Biden to steer a brand new, nationwide “Moonshot” initiative to eliminate most cancers as we all know it. The goal is to double the speed of progress towards cancer, reaching in 5 years what otherwise would have taken ten. The White House introduced a $1 billion initiative to jumpstart this work. TCGA researchers accomplished entire-exome sequencing, which examines the protein-coding regions of the genome, on an unprecedented 316 tumors. November 10, 2010â€"Researchers discovered mutations in a specific gene that affects the treatment prognosis for some sufferers with acute myeloid leukemia, an aggressive blood most cancers that kills 9,000 Americans annually. October 7, 2009â€"Researchers found that a small RNA molecule, often known as a microRNA, might assist physicians identify liver most cancers sufferers who, regardless of their poor prognosis, might respond properly to therapy with a organic agent called interferon. 2015â€"President Obama announced a analysis effort focusing on bringing precision drugs to many elements of healthcare. $216 million in funding was allocated to NCI and FDA for the initiative. June 1, 2015â€"Investigators for the nationwide trial, NCI-MATCH , introduced that the precision medication trial will open to affected person enrollment. NCI-MATCH analyzes patients’ tumors to determine whether or not they contain gene abnormalities for which a targeted drug exists and assigns remedy primarily based on the abnormality. The examine was co-developed by NCI and the ECOG-ACRIN Cancer Research Group, a cooperative group that was fashioned by the merger of the Eastern Cooperative Oncology Group and the American College of Radiology Imaging Network .

Friday, September 18, 2020

Apa

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Thursday, September 17, 2020

Smart Papers For Sale; 200 Jobs At Risk

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Tuesday, August 25, 2020

Use of Scientific Management in the 21st Century

Utilization of Scientific Management in the 21st Century Roberta Larkins Jones International University April 14, 2010 Abstract The nineteenth and twentieth Century gives the establishment of the move in the executives displaying. Frederick Taylor, Henry Gantt, and Lillian Gilbreth gave incredible understanding into the requirement for a change in outlook in business. The components of this move structure the premise of the four standards of Scientific Management. The standards of Scientific Management and their utilization in the 21st Century are the components of this paper. Utilization of Scientific Management in the 21st Century The administration of an association that has an auxiliary framework which plainly characterizes the elements of the offices, gatherings, and people can be characterized by the term Scientific Management started by Frederick Taylor. (Nelson, 2003, p. 1) The Encyclopedia for Business (n. d. ) characterizes Scientific Management as â€Å"methods planned for deciding the most ideal route for work to be finished. (n. d. , pg 6). While the underlying utilization of Scientific Management in managing issues of effectiveness and profitability is established throughout the entire existence of the executives hypothesis during the nineteenth Century and from the get-go in the twentieth Century, the equivalent authoritative needs are apparent in business today and the use of the essentials of Scientific Management can be utilized to successfully increment both proficiency and efficiency in a 21st Century association. The Pioneers Frederick Taylor, known as ‘the most in? ential business master of the twentieth century’ (154), started his excursion into business in an apprenticeship to a patternmaker for a siphon fabricating organization in Philadelphia. (Wren, 2004, 121) It is here Taylor has the chance to see firsthand what the workers are encountering and make note of the components of talk. Wren portrays the conditions as â€Å"worker limitation of yield, poor administration, and absence of congruity among work and management† (2004, p. 122). As Taylor kept on progressing in his vocation, he stood observer to occurrences of these equivalent conditions in the workers at Midvale Steel Company. It is during this time in his vocation alongside his craving to change those working conditions that he started the work in Scientific Management that permits him to positively shape administrative history. Henry Gantt, likewise a mechanical architect, worked with Taylor for a long time and both were accomplices in the advancement the idea of logical administration, in spite of the fact that Taylor is all the more broadly perceived for the model. Gant’s impact gave fuel to a superior comprehension of human instinct in the workforce by improving worker portrayal plans , improving the acts of HR, and collaboration by work the executives,. Wren, 2004, p. 165) The human side of the executives is likewise the focal point of works by Lillian Gilbreth, who is regularly called the principal woman of the board. (Pioneers of Management, n. d. , p7). Together they were the main impetus in the utilization of Scientific Management and the formation of human asset standards inside an associ ation. The Fundamentals Taylor saw business as â€Å"a arrangement of human participation that will be fruitful just if all concerned work toward a typical goal† (Wren, 2004, p. 125). The four standards of Scientific Management address the underlying worries that Taylor saw. Hodgetts and Greenwood (1995) share the four essentials as (1) Develop a science for every component of the person’s work, hence supplanting the old general guideline, (2) Scientifically select, and afterward train, instruct, and build up the specialist, (3) Heartily help out the faculty in order to guarantee that the entirety of the work is done as per the standards of the science that it has been created, and (4) Management should assume control over all the work for which it is best fitted than the laborers, and permit the last to deal with the rest. (1995, p. 18-221) These essentials can likewise move into the goals of the first conditions by expanding specialist efficiency, viable administration, and making an agreeable connection among the board and laborer. Expanding Worker Productivity Embedded into standards one and two, are contemplations for sound human-asset the executives today. Taylor foreseen the idea of coordinating the capacities of a specialist to a relegated activity. (Wren, 2004, p. 129) Instead of building up their own way to deal with work through understanding, the representative will figure out how to do it the correct way. Hodgetts and Greenwood, 1995, p. 218) or more prepared in more up to date methods which will permit the worker to be progressively profitable in their yield. Taylor’s faith in profitability was grounded in the thought â€Å"the genuine potential for expanded yield was not ‘working harder’ yet ‘working more brilliant. ’† (Wren, 2009, p. 128). Hodgetts and Greenwood (1995) portray the capacity to expand profitability â€Å"by preparing, educating, and building up their work force, this quality-driven association had the option to accomplish significant increments in effectiveness and cost investment funds. † (1995, p. 220). Powerful preparing evaluates the preparation need inside an association, prepares the representative with cutting edge or progressively effective devices and strategies, at that point permits the worker to come back to the association and use their new abilities in this manner expanding the profitability of the worker. Powerful Management The third standard in logical administration is introduced by the use of viable administration in an association. As per Taylor, the rule object of the executives is to make sure about the greatest level or flourishing for both boss and every worker. (Wren, 2009, p. 48). Regardless of whether this is finished by 21st Century ability the board programs including rewards and advancements, or nineteenth Century prize and acknowledgment framework, the incorporation of something that shows to the representative that the individual in question is esteemed is basic. Agreeable Relationship The fourth guideline of logical administration is to uphold the hypo thesis of laborers and the executives meeting up so as to run a fruitful association. Some portion of this exertion is in permitting the laborers to turn out to be a piece of the arrangements required accomplish more significant levels of proficiency and profitability. Darmody (2007) shares that administration presently understands that whenever laborers are allowed the chance to propose thoughts, they will work more enthusiastically in the execution of and confirmation in the achievement of them. (2007, p. 23). Taylor’s perspective on this is nonstop improvement exertion. End The four standards of logical administration were significant in the nineteenth century and keep on being significant in the 21st Century in business. An association that has an objective to stay fruitful and serious must fuse every one of the four parts into the key arrangement. As the outlook of the executives movements to manage the inner and outer powers of business in pushing ahead, a glance back at the vision of Taylor, Gantt, and Gilbreth will help the association to succeed. References Darmody, P. (2007). Henry L. Gantt and Frederick Taylor: The Pioneers of Scientific Management. AACE International Transactions, 15. 1-15. 3. Recovered from Business Source Premier Database. Hodgetts, R. , and Greenwood, R. (1995). Frederick Taylor: Alive and Well and Ready for the 21st Century. Foundation of Management Best Papers Proceedings, 218-222. Recovered from Business Source Premier Database. Nelson, D. , (2003, Jan) Scientific Management, Dictionary of American History, Retrieved from http://www. highbeam. com/doc/1G2-3401803768. html Pioneers of Management. (n. d. ). In Encyclopedia of Business (second ed. ). Recovered from http://www. referenceforbusiness. com/the executives/Or-Pr/Pioneers-of-the executives. html Wren, D. , (2009) the development of the executives thought (sixth Ed). Hoboken, NJ: John Wiley and Sons